License
LPN
Hourly Avg.
Hourly Avg. Range
$
44.78
$
-
$
Shift Type
Per Diem
Date Posted
February 1, 2026
Valid Through
April 4, 2026

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Job Description

Join our growing network of dedicated and experienced licensed practical nurses (LPNs) finding high-paying per diem job opportunities in

Seneca

,

South Carolina

.

LPNs provide basic nursing care and treatment to patients under the supervision and guidance of nursing supervisors or physicians. With Nursa, practical nurses can work in a variety of settings, including skilled nursing facilities (SNFs), long-term care (LTC) centers, assisted living facilities (ALFs), hospitals, home healthcare services, physicians’ offices, and more.

LPN responsibilities:

Although specific job duties will vary depending on your working location, the responsibilities of an LPN in any healthcare setting generally include the following:

  • Monitor patient health by checking vital signs, including pulse rate, blood pressure, and body temperature
  • Monitor patient diet, intake, and output
  • Provide basic patient care and comfort, including changing bandages, repositioning, and helping with activities of daily living, such as bathing and eating
  • Assist patients with mobility, transfers, and positioning
  • Administer medications as prescribed and as permitted by state licensure and facility policy
  • Assist with oxygen therapy and monitor oxygen delivery as ordered
  • Perform or assist with clinical tests, such as phlebotomy duties and urinalysis, as permitted by the state's scope of practice
  • Administer vaccinations as permitted by state and facility regulations
  • Remove sutures or staples as permitted by the state's scope of practice
  • Monitor patients after treatments and document changes in condition
  • Collect patient information and record medical histories using electronic health/medical record (EHR/EMR) systems, as required
  • Document patient care and maintain up-to-date health records
  • Observe and report changes in a patient's condition to registered nurses (RNs), advanced practice registered nurses (APRNs), or physicians
  • Maintain patient confidentiality and comply with privacy requirements
  • Educate patients and their families on care routines, treatments, and next steps as appropriate
  • Offer emotional support to patients and their families
  • Prepare patients for discharge or transfer by completing care tasks, handoff reports, and patient education
  • Assist in supervising or training certified nursing assistants (CNAs) or nurse aides
  • Assist with patient transport within or between care areas
  • Maintain safety standards, including fall prevention practices, proper equipment use, and compliance with facility procedures
  • Follow hygiene and infection control procedures
  • Monitor supply levels and assist with inventory management

LPN qualifications:

The following qualifications include requirements for LPN licensure and capabilities typically expected by healthcare facilities posting shifts on the Nursa platform:

  • Complete a state-approved practical nursing educational program (high school diploma or equivalent required for program admission)
  • Pass the National Council Licensure Examination for Practical Nurses (NCLEX-PN)
  • Hold a current and unencumbered practical nurse license in the state of practice
  • Maintain license by fulfilling continuing education requirements
  • Maintain current Basic Life Support (BLS) or CPR certification as required by facility or role
  • Keep immunization records up to date, as required by state and facility policies
  • Pass required federal, state, and local background checks
  • Demonstrate excellent clinical skills, including the ability to take accurate vital signs, proficiently administer medications, and perform basic medical procedures safely and competently
  • Show strong attention to detail and observational skills to identify subtle changes in a patient's health
  • Demonstrate excellent verbal and written communication skills to effectively communicate with patients, families, and the healthcare team
  • Provide compassionate and reliable care with sensitivity and respect for patients
  • Work effectively both independently and as part of a team
  • Manage time effectively to handle multiple tasks and prioritize patient needs
  • Apply strong organizational and problem-solving skills
  • Adapt quickly to different healthcare settings, units, teams, patient populations, and workflows
  • Maintain physical stamina to stand for long periods, bend, stoop, and perform physically demanding tasks such as lifting and moving patients
  • 1+ years of experience as an LPN is preferred for per diem roles, though no minimum experience is required

Additional certifications may be required depending on the type of facility, and specific role, including wound care, gerontology, rehabilitation, hospice or palliative care, IV therapy, pharmacology, or long-term care.

Working as a PRN LPN on the Nursa platform can offer opportunities to pick up shifts in various settings, maintain a flexible schedule, and supplement income while supporting work-life balance.

LPN benefits:

LPNs who pick up shifts with Nursa enjoy more than flexibility—they gain real advantages that make every shift easier and every payday faster.

  • Get paid instantly with Nursa Direct: Access your earnings as soon as your shift is verified.
  • Stay covered with Hooray Health: Explore affordable supplemental coverage for peace of mind between shifts.
  • Train confidently with ShiftReady: Complete facility-required training and skill refreshers before your next assignment.
  • Simplify taxes with Keeper Tax: Automatically track deductions and manage write-offs throughout the year.

These benefits are designed to help you take control of your work, your time, and your financial future.

Get started in minutes:
With Nursa, you decide when, where, and how often you work. Joining takes only a few minutes—no long applications, no staffing agency paperwork.
  1. Create your free account: Download the app or sign up online.
  2. Upload your licenses and certifications: Verify your credentials once.
  3. Complete free background checks: Meet basic facility vetting requirements quickly.
  4. Add your payment information: Set up your preferred payout method to get paid fast.
  5. Make your profile stand out: Highlight your nursing experience and skills.
  6. Request shifts: Browse openings near you and start earning fast.

About Required LPN License:

Licensed practical nurses (LPNs) are in high demand throughout the United States. With PRN nursing jobs, LPNs have the luxury of choosing when and where they want to work while earning competitive hourly wages.

About Location:

South Carolina, nicknamed the "Palmetto State," is known for its coastal beaches, mountainous terrain, and varied suburban and rural landscapes. It's a popular destination for both tourists and nursing professionals as there are plentiful per diem opportunities throughout the state. It's temperate climate and southern hospitality makes it an enjoyable place to work and live.

*This job posting is representative of the type of shifts available in this area on the Nursa platform.

Pick Up a Job Today

Nursa is always looking for LPN nurses to pick up per diem shifts

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GO BEYOND A SINGLE JOB

Choose Multiple LPN Shifts on Your Schedule

Nursa isn't just about finding a job; it's about crafting your ideal work schedule by selecting shifts. Once you create a Nursa profile, you will experience the convenience of scheduling shifts in real-time.

Seneca, South Carolina, offers abundant PRN nursing opportunities with competitive pay, diverse experiences, and the freedom to craft your ideal work schedule. Nursa can help nurses find per diem shifts at local healthcare facilities, allowing them to choose jobs and track their work history.

Want to pick up high-paying PRN jobs in South Carolina? Nursa is a marketplace that connects nurses and CNAs with shifts near them.

Average LPN
Pay in Seneca, South Carolina

$
42.52
/hour
$
23.01
Low
$
43
Average
$
50
High

To become a licensed practical nurse (LPN) and maintain licensure, a candidate must complete a state-approved educational program, pass a standardized test for LPNs, and fulfill other state-specific requirements.

Pick Up a Job Today

Nursa is always looking for LPN nurses to pick up per diem shifts

Join Nursa

Table of Contents

PRN LPN Jobs in Seneca┃Flexible and Well-Paid

Flexible nursing careers are rising, and PRN LPN jobs in Seneca, South Carolina, are no exception. With the increased demand for healthcare services, the need for skilled nurses to fill shifts temporarily has grown. PRN LPN jobs, also known as per diem shifts, offer nurses the flexibility to choose when and where they want to work. LPNs have the opportunity to work with various populations, from newborns to the elderly, and can enjoy nature, shopping, or music in between shifts. If you are interested in learning more about PRN LPN jobs with Nursa, read on!

From the Hospital to Home Health

One of the greatest benefits of PRN LPN jobs is the opportunity to work in a variety of settings, including hospitals, assisted living facilities, and home health agencies. Home health is a growing field that allows nurses to provide care to patients in the comfort of their own homes. Seneca is home to several home health agencies, such as the following:

  • OMH Home Heath is part of the Omnicare Medical Group. Their focus is on providing skilled nursing, therapy, and other healthcare services to patients in the comfort of their own homes.
  • Medi Home Hospice provides hospice services to terminally ill individuals and their families. It offers patients physical, emotional, and spiritual care in their homes, nursing homes, or other care facilities. Its team of healthcare professionals supports patients and their families during the end-of-life journey.
  • Kindred at Home, a home health and hospice agency, offers a range of services to help seniors and individuals with chronic illnesses or disabilities. These include skilled nursing, therapy, personal care, and hospice care. The agency also offers specialized programs such as dementia care and care for veterans.

Working in home health allows LPNs to build close relationships with their patients and their families, and there are many more agencies in the surrounding area.

The Diverse Patient Population Awaiting LPNs

As an LPN in Seneca, you will have the opportunity to work with a wide range of patients, from seniors at the nursing homes and home health to newborns at Prisma Health Oconee Hospital's new neonatal intensive care unit (NICU) officially opened in March 2024. This diversity allows for constant learning and growth in your nursing practice. From caring for premature infants in the neonatal intensive care unit to providing end-of-life care for the elderly, LPNs play a vital role in the healthcare team. The experience gained from working with different patient populations is invaluable and can open up doors for future career opportunities.

Opportunities in the Surrounding Area

If you are looking for PRN LPN jobs beyond Seneca, several cities within driving distance offer various healthcare job opportunities. Greenville and Spartanburg, both under a one-hour drive and Newberry, a little farther away, all offer PRN job opportunities for LPNs as well as RNs and CNAs. The South Carolina Nursing Guide provides clear information on salaries and the demand for nurses all over the state.

Importance of LPNs on Health Teams

LPNs play a crucial role in the healthcare team, working alongside registered nurses, doctors, and other healthcare professionals. Their hands-on patient care and attention to detail ensure patients receive the best care possible. LPNs also provide emotional support to both patients and their families, making them an essential part of the healthcare team.

Stay strong. All nurses need time and places they enjoy and can relax on their off-time in order to take care of themselves.

Enjoy Nature, Shopping, or Music Between Shifts

Seneca is located in a beautiful area surrounded by nature and offers opportunities for outdoor activities. Check out some of the local parks to enjoy in between shifts, such as:

If you prefer shopping, visit the M. Tannery and Son's antique mall, located in historic downtown Seneca, or the nearby Keowee Shopping Center. And for music lovers, be sure to catch Jazz in the Alley, a live concert series held every summer.

What Does Nursa Do For You?

Nursa connects healthcare facilities with qualified nurses. As a Nursa nurse, you have the flexibility to choose when and where you want to work. You can browse PRN LPN jobs and apply for shifts directly through the Nursa app. Nursa also offers competitive pay rates, weekly direct deposits, and the option to build your professional network by working in various healthcare settings.

How Can I Find PRN LPN Jobs near Me?

Finding PRN LPN jobs near you is easy with Nursa. Download Nursa on your mobile device and create a profile. Once your profile is complete, start browsing and applying for available shifts in Seneca and surrounding areas. Don't wait any longer; download the Nursa app today and start building your flexible nursing career!

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