License
LPN
Hourly Avg.
Hourly Avg. Range
$
50.69
$
-
$
Shift Type
Per Diem
Date Posted
February 1, 2026
Valid Through
March 22, 2026

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Job Description

Join our growing network of dedicated and experienced licensed practical nurses (LPNs) finding high-paying per diem job opportunities in

Simpsonville

,

South Carolina

.

LPNs provide basic nursing care and treatment to patients under the supervision and guidance of nursing supervisors or physicians. With Nursa, practical nurses can work in a variety of settings, including skilled nursing facilities (SNFs), long-term care (LTC) centers, assisted living facilities (ALFs), hospitals, home healthcare services, physicians’ offices, and more.

LPN responsibilities:

Although specific job duties will vary depending on your working location, the responsibilities of an LPN in any healthcare setting generally include the following:

  • Monitor patient health by checking vital signs, including pulse rate, blood pressure, and body temperature
  • Monitor patient diet, intake, and output
  • Provide basic patient care and comfort, including changing bandages, repositioning, and helping with activities of daily living, such as bathing and eating
  • Assist patients with mobility, transfers, and positioning
  • Administer medications as prescribed and as permitted by state licensure and facility policy
  • Assist with oxygen therapy and monitor oxygen delivery as ordered
  • Perform or assist with clinical tests, such as phlebotomy duties and urinalysis, as permitted by the state's scope of practice
  • Administer vaccinations as permitted by state and facility regulations
  • Remove sutures or staples as permitted by the state's scope of practice
  • Monitor patients after treatments and document changes in condition
  • Collect patient information and record medical histories using electronic health/medical record (EHR/EMR) systems, as required
  • Document patient care and maintain up-to-date health records
  • Observe and report changes in a patient's condition to registered nurses (RNs), advanced practice registered nurses (APRNs), or physicians
  • Maintain patient confidentiality and comply with privacy requirements
  • Educate patients and their families on care routines, treatments, and next steps as appropriate
  • Offer emotional support to patients and their families
  • Prepare patients for discharge or transfer by completing care tasks, handoff reports, and patient education
  • Assist in supervising or training certified nursing assistants (CNAs) or nurse aides
  • Assist with patient transport within or between care areas
  • Maintain safety standards, including fall prevention practices, proper equipment use, and compliance with facility procedures
  • Follow hygiene and infection control procedures
  • Monitor supply levels and assist with inventory management

LPN qualifications:

The following qualifications include requirements for LPN licensure and capabilities typically expected by healthcare facilities posting shifts on the Nursa platform:

  • Complete a state-approved practical nursing educational program (high school diploma or equivalent required for program admission)
  • Pass the National Council Licensure Examination for Practical Nurses (NCLEX-PN)
  • Hold a current and unencumbered practical nurse license in the state of practice
  • Maintain license by fulfilling continuing education requirements
  • Maintain current Basic Life Support (BLS) or CPR certification as required by facility or role
  • Keep immunization records up to date, as required by state and facility policies
  • Pass required federal, state, and local background checks
  • Demonstrate excellent clinical skills, including the ability to take accurate vital signs, proficiently administer medications, and perform basic medical procedures safely and competently
  • Show strong attention to detail and observational skills to identify subtle changes in a patient's health
  • Demonstrate excellent verbal and written communication skills to effectively communicate with patients, families, and the healthcare team
  • Provide compassionate and reliable care with sensitivity and respect for patients
  • Work effectively both independently and as part of a team
  • Manage time effectively to handle multiple tasks and prioritize patient needs
  • Apply strong organizational and problem-solving skills
  • Adapt quickly to different healthcare settings, units, teams, patient populations, and workflows
  • Maintain physical stamina to stand for long periods, bend, stoop, and perform physically demanding tasks such as lifting and moving patients
  • 1+ years of experience as an LPN is preferred for per diem roles, though no minimum experience is required

Additional certifications may be required depending on the type of facility, and specific role, including wound care, gerontology, rehabilitation, hospice or palliative care, IV therapy, pharmacology, or long-term care.

Working as a PRN LPN on the Nursa platform can offer opportunities to pick up shifts in various settings, maintain a flexible schedule, and supplement income while supporting work-life balance.

LPN benefits:

LPNs who pick up shifts with Nursa enjoy more than flexibility—they gain real advantages that make every shift easier and every payday faster.

  • Get paid instantly with Nursa Direct: Access your earnings as soon as your shift is verified.
  • Stay covered with Hooray Health: Explore affordable supplemental coverage for peace of mind between shifts.
  • Train confidently with ShiftReady: Complete facility-required training and skill refreshers before your next assignment.
  • Simplify taxes with Keeper Tax: Automatically track deductions and manage write-offs throughout the year.

These benefits are designed to help you take control of your work, your time, and your financial future.

Get started in minutes:
With Nursa, you decide when, where, and how often you work. Joining takes only a few minutes—no long applications, no staffing agency paperwork.
  1. Create your free account: Download the app or sign up online.
  2. Upload your licenses and certifications: Verify your credentials once.
  3. Complete free background checks: Meet basic facility vetting requirements quickly.
  4. Add your payment information: Set up your preferred payout method to get paid fast.
  5. Make your profile stand out: Highlight your nursing experience and skills.
  6. Request shifts: Browse openings near you and start earning fast.

About Required LPN License:

Licensed practical nurses (LPNs) are in high demand throughout the United States. With PRN nursing jobs, LPNs have the luxury of choosing when and where they want to work while earning competitive hourly wages.

About Location:

South Carolina, nicknamed the "Palmetto State," is known for its coastal beaches, mountainous terrain, and varied suburban and rural landscapes. It's a popular destination for both tourists and nursing professionals as there are plentiful per diem opportunities throughout the state. It's temperate climate and southern hospitality makes it an enjoyable place to work and live.

*This job posting is representative of the type of shifts available in this area on the Nursa platform.

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Nursa is always looking for LPN nurses to pick up per diem shifts

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GO BEYOND A SINGLE JOB

Choose Multiple LPN Shifts on Your Schedule

Nursa isn't just about finding a job; it's about crafting your ideal work schedule by selecting shifts. Once you create a Nursa profile, you will experience the convenience of scheduling shifts in real-time.

Simpsonville, South Carolina offers a diverse and thriving community with numerous parks, restaurants, and shopping options. Its proximity to larger cities, combined with its small-town charm, makes it an ideal place to live and work. One of the main draws for PRN nurses and nursing assistants to this city is the opportunity for flexible scheduling and picking PRN jobs. These shifts can be highly rewarding for RNs, LPNs, and CNAs, as they allow them to gain valuable experience and contribute to the health and well-being of the community.

Want to pick up high-paying PRN jobs in South Carolina? Nursa is a marketplace that connects nurses and CNAs with shifts near them.

Average LPN
Pay in Simpsonville, South Carolina

$
42.52
/hour
$
23.01
Low
$
43
Average
$
50
High

To become a licensed practical nurse (LPN) and maintain licensure, a candidate must complete a state-approved educational program, pass a standardized test for LPNs, and fulfill other state-specific requirements.

Pick Up a Job Today

Nursa is always looking for LPN nurses to pick up per diem shifts

Join Nursa

High-Paying PRN LPN Jobs in Simpsonville, South Carolina

Are you a Licensed Practical Nurse (LPN) looking for a flexible and rewarding career? Well, look no further because Simpsonville, South Carolina, has plenty of PRN (as needed) LPN jobs available. With Nursa, a modern nursing job platform, you can easily find and apply for PRN LPN jobs with just a few clicks.

What Does Daily Life in Simpsonville, South Carolina Look Like?

Simpsonville is a charming southern city located in Greenville County, South Carolina. It is situated in the foothills of the Blue Ridge Mountains and is known for its picturesque landscapes and warm hospitality. With a population of over 25,000, Simpsonville offers the perfect blend of small-town charm and big-city amenities, making it an ideal place to live and work.

Simpsonville is a great place for outdoor enthusiasts. You can explore the many parks and nature trails in the area, such as Heritage Park, which features a playground, picnic areas, and a lake for fishing. Or you could visit the nearby Golden Park, which offers walking trails, sports fields, and a spray park for the kids.

If you're a history buff, you'll enjoy visiting the South Carolina Museum of Revolutionary War History, which displays artifacts and documents from the city's past. And if you're a foodie, Simpsonville has a growing food scene, with various restaurants offering a variety of cuisines to satisfy your taste buds.

What Does Working PRN Mean?

Before diving into the opportunities for PRN LPN jobs in Simpsonville, let's first understand what PRN means. PRN, or "as needed," refers to a flexible job schedule where employees work on an as-needed basis. This type of work is well-suited for individuals who prefer a more flexible schedule, allowing for a work-life balance that suits their needs.

Where are Some Healthcare Facilities LPNs Can Work?

In Simpsonville, PRN LPN jobs are available in various healthcare settings, including hospitals, clinics, and long-term care facilities. Some of the top healthcare facilities to work for as an LPN include Prisma Health Hillcrest Hospital, Laurens County Healthcare System, and Prisma Health Greer Memorial Hospital. There are also a few nursing homes, such as Simpsonville Post-Acute (formerly Simpsonville Rehabilitation and Healthcare Center) and The Springs at Simpsonville.

Advantages of Working PRN LPN Jobs

One of the biggest advantages of working PRN LPN jobs is the flexibility it offers. You can choose when and where you want to work, allowing for a better work-life balance. This flexibility also means you can earn more money by picking up shifts on your days off or evenings.

Another advantage of working as a PRN is the opportunity to gain more experience in different specialties and healthcare settings, making you a well-rounded nurse. And with Nursa, you'll have access to multiple job opportunities in and around Simpsonville, as well as nearby cities like Greenville, Greer, and Mauldin, South Carolina.

What Qualities Should a Good PRN LPN Nurse Have?

To excel in PRN LPN jobs, you'll need to possess certain qualities that make you stand out as a nurse. First and foremost, you should have excellent communication skills, as you'll be working closely with patients and other healthcare professionals. You should also be detail-oriented, compassionate, and able to handle stress well.

You should also have the ability to work independently and make critical decisions quickly. As a PRN LPN, you'll need to adapt to different work settings and patient needs, so being flexible and able to think on your feet is crucial.

Working PRN: What to Expect on Shift

Nursa's user-friendly app allows nurses to easily browse and apply for PRN LPN jobs in Simpsonville and surrounding areas. As soon as you are offered a shift, you'll receive all the necessary information, including the facility name, shift details, and pay rate.

On your shift, you can expect to work closely with registered nurses (RNs) and certified nursing assistants (CNAs) to provide patient care. As a PRN LPN, you'll have a vital role in ensuring the well-being of patients and assisting with their recovery.

Pick up PRN LPN Jobs in Simpsonville Today and Earn More!

Overall, Simpsonville, South Carolina, offers plenty of opportunities for PRN LPNs to work in a variety of healthcare settings and specialties. With the flexibility and experience that PRN jobs offer, you can build a fulfilling and rewarding nursing career in this charming southern city.

So, if you're an LPN looking for a change of pace or just starting your nursing career, consider picking up PRN LPN jobs in Simpsonville with Nursa. Download the app today and start browsing and applying for PRN LPN shifts in this beautiful city and neighboring areas.

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