Deadly care: The chilling true story behind "The Good Nurse"

A nurse holding a paper with a question mark
Written by
Nursa Admin
Category
Lifestyle
June 8, 2025

Key takeaways:

  1. Discover how dangerous gaps in hospital oversight allowed a serial killer nurse to go undetected for years.
  2. Learn how whistleblower Amy Loughren’s bravery exposed both a murderer and serious flaws in the healthcare system.
  3. Realize the critical importance of transparent incident reporting and rapid action when suspicions arise.
  4. Understand how bureaucracy, misplaced trust, and fear of litigation can put patient safety at risk.
  5. See how inspiring individual vigilance and empowering nurses can drive vital reforms in healthcare settings.

When you hear "nurse," you likely picture compassion, healing touch, and round-the-clock care. So what do you do when the one individual whose job it is to save lives is silently taking them instead? If you've watched the Netflix thriller The Good Nurse, chances are you're wondering: What true story is The Good Nurse based on? Buckle up—because the true story is just as suspenseful, if not more sinister, than the one on your television screen.

Did you see or hear about The Good Nurse? A lot of people are enjoying the series despite the goosebumps. But did you know whose real story was behind its chapters? Keep reading and you will find out! 

Table of Contents

"The Good Nurse" true story: Fact over fiction

So what true story is The Good Nurse? The movie is an adaptation of the real-life horror story of Charles Cullen, a serial killer and retired registered nurse, and Amy Loughren, a nurse who risked everything to bring him down. Far from fiction, the dark tale is documented in Charles Graeber's non-fiction book adaptation of the same name, The Good Nurse, which inspired the movie.

Charles Cullen is one of the most prolific serial killers among healthcare workers in the United States. His crimes went unnoticed for over 16 years, during which he had been employed in a number of hospitals in New Jersey and Pennsylvania.

Meet Charles Cullen: The serial killer in scrubs

The Charles Cullen case shocked the world. Cullen was seemingly a bland nurse who took advantage of his patient access and medical knowledge to administer lethal doses of such drugs as insulin and digoxin. Although he claimed that he was "easing suffering," the majority of his victims were not dying.

According to the Charles Cullen biography, he claimed to have murdered up to 40 patients, though police would later estimate that the number could have been in excess of 400. Yep, you heard that right: 400. That would make him one of the most prolific killers of nurses in true crime history.

So, where did Charles Cullen work? He floated through at least nine hospitals. Every time suspicions were aroused, hospitals quietly let him go—sometimes without even calling the police. This evil loophole allowed the Charles Cullen hospital murders to run out of control for years.

Amy Loughren: The whistleblower hero

Enter Amy Loughren, a single mother and nurse with a heart condition. She worked at the same hospital as Cullen in New Jersey, Somerset Medical Center. She was unwittingly working alongside a killer.

When she was questioned by police, she was afraid. Far from turning a blind eye, she came closer. Using her insider information and friendship with Cullen, she wore a wire discreetly and gathered crucial evidence that resulted in his arrest.

Amy Loughren nurse-hero proved that one person could make a difference. She displayed bravery that resulted in a serial killer's capture and exposed fundamental flaws in the healthcare system.

Read more stories of real nurses making a difference and discover the characteristics of a nurse who actually live greatness.

Killer nurse Netflix version: How realistic is it?

Netflix's The Good Nurse stays incredibly true to the facts. The film illustrates how Amy Loughren Charles Cullen worked in conjunction with one another and how she assisted law enforcement officers in arresting him. A little dramatic license was utilized (as is with any movie), but the actual story of The Good Nurse still stands.

The emotional burden, the moral issues, and the dramatic moments portrayed in the film are actually the real-life tension Amy experienced. To have a better plunge into how Netflix dramatized things, continue reading this community thread on patient safety in The Good Nurse.

Charles Cullen documentary and other media

If you're fascinated (and perhaps horrified), there's more to see. The Charles Cullen documentary piece on Nurses Who Kill and a variety of true crime podcasts lay out the horrific investigation. Still, the Netflix movie is among the most easily accessible—and chilling—interpretations.

Are you in search of nurse content with a more varied tone? Here's where to stream Nurse Jackie free from buying it, or check out this list of nurse films.

Why this tale holds up

This is not just a scary historical story. The real events upon which The Good Nurse movie is based reveal frailties in the healthcare system's ability to detect potentially dangerous people. Cullen slipped through the cracks due to bureaucratic failures, misplaced trust, and fear of lawsuits.

The actual nurses halt serial killer isn't just a front-page story—it's an eye-opener. Amy Loughren's courage spurred policy reforms and empowered a new generation of nurses to be vigilant. To learn about how nurses are pushing boundaries in new care, find out these nursing trends and technology advances.

The aftermath: Charles Cullen criminal case and sentencing

The case of Charles Cullen finally came to a close in 2006. He was sentenced to 11 consecutive life sentences and will never be eligible for parole. The public was shocked to learn that his reign of terror had lasted so long—and that so many hospitals had not acted.

Amy Loughren's been an advocate for patient safety and mental health ever since going through the post-whistleblower experience herself. She notes the ongoing stress that this ordeal caused her. Her voice is a reminder of how much individual power there can be.

Good nurse fact vs. fiction: What's real?

While The Good Nurse dramatizes a few of the conversations and compresses timelines, the emotional center stays true to real events. Amy and Charles's relationship, the slow acceptance of what's occurring around her, and her final bravery are all based on confirmed events.

For further discussion of film accuracy, visit this active community forum on the true story behind the movie.

What did the true story of "The Good Nurse" teach us?

So again, what true-life saga is The Good Nurse based on? It's a serial killer of medical staff, Charles Cullen, and the pivotal role played by one nurse—whistleblower Amy Loughren, in bringing him down.

The real story The Good Nurse, not only exposes the horrors of unchecked power, but also the incredible ability that lies in plain heroes. Amy's story is one of hope, courage, and the need for ethical sensitivity. 

Just like Amy Loughren, nurses have the power to change lives—even save them. Download the Nursa App today, to start making a difference in the lives of patients.

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Nursa Admin
Blog published on:
June 8, 2025

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