How to change central line dressing: A guide for nurses

a central line kit
Written by
Nursa Admin
Category
Guides
July 23, 2025

Key takeaways:

Follow these essential practices to ensure safe central line dressing changes and prevent life-threatening complications in your patients.

  • Follow strict timing protocols: For optimal infection prevention, replace transparent dressings every seven days, while gauze dressings require changes every forty-eight hours. Any dressing that becomes compromised—whether wet, loose, or soiled—demands immediate replacement regardless of the standard schedule.
  • Maintain sterile technique: Proper hand hygiene serves as the foundation for infection prevention. Both the healthcare provider and patient must wear masks during the procedure. Using sterile supplies and maintaining aseptic technique throughout the process is crucial for preventing dangerous bloodstream infections when learning how to do a sterile dressing change of a central line.
  • Clean with chlorhexidine: Apply the solution using deliberate back-and-forth motions for thirty seconds minimum. Allow complete drying for sixty seconds before proceeding. Avoid wiping or blotting the area after application, as this reduces the antiseptic effectiveness.
  • Monitor infection signs: Understanding how to change a central line dressing includes vigilant monitoring for potential complications. Watch for temperature elevations above 100.4 degrees Fahrenheit, redness, swelling, unusual drainage, or warmth at the insertion site. Report these warning signs to a physician immediately if observed.
  • Document thoroughly: Comprehensive documentation supports continuity of care and meets facility requirements. Record the date, time, detailed site assessment findings, specific dressing type used, and all pertinent observations during the procedure for changing a central line dressing.

Central line infections result in 12-25 percent mortality rates, but following proper nursing practices for how to do a central line dressing change prevents up to seventy percent of these serious infections. Your meticulous attention during this routine yet critical procedure directly impacts patient safety and outcomes.

Learning how to change a central line dressing effectively is a critical skill that every registered nurse must master. 

Central venous catheters are essential medical devices used to deliver various long-term treatments, from extended antibiotic therapy and nutritional support to dialysis and cancer medications.

When considering how to change a central line's sterile dressing, both timing and proper technique are vital elements. Healthcare providers typically need to change transparent dressings every seven days, while gauze dressings require more frequent changes every two days. 

However, any dressing that becomes compromised—whether it's wet, loose, or visibly soiled—must be changed immediately, regardless of when the last change occurred. This specialized procedure requires proper training since it's not considered routine care across all healthcare settings.

In this comprehensive guide, we'll explore the complete process of how to do a central line dressing change using evidence-based techniques. 

From gathering necessary supplies to proper documentation, we'll cover every essential step required to maintain catheter integrity and prevent potentially dangerous infections. 

Let's ensure optimal patient outcomes through proper central line management.

Table of Contents

Understanding central line dressings

Central venous catheters play an indispensable role in modern healthcare, particularly for patients requiring extended treatment. Before learning how to change a central line dressing, understanding these devices and their maintenance is crucial.

What is a central line?

Central venous catheters (CVCs) are specialized medical devices consisting of long, flexible tubes that healthcare providers insert into a major vein, typically located in the neck, chest, arm, or groin area. 

Unlike standard peripheral IVs placed in smaller arm or hand veins, central lines access larger blood vessels near the heart, specifically targeting the vena cava. These advanced catheters serve multiple critical purposes in patient care, enabling healthcare teams to deliver medications, fluids, nutritional support, and blood products efficiently. 

They also provide convenient access for blood sampling, monitoring vital cardiovascular parameters, and performing specialized procedures like transvenous pacing.

The external portion of a central line typically terminates in one of two ways—either with an accessible hub that remains visible above the skin's surface or through a portal system that creates a small, quarter-sized bump underneath the skin for more discreet access. 

Compared to traditional peripheral IVs, CVCs offer significant advantages, including reduced need for repeated needle sticks, decreased patient discomfort during treatments, and reliable long-term vascular access.

Why are dressing changes important?

Proper central line dressing changes are crucial primarily because they prevent central line-associated bloodstream infections (CLABSIs). 

These serious complications result in the highest number of preventable deaths among all healthcare-associated infections, with mortality rates between 12 and 25 percent. The encouraging news is that implementing evidence-based care practices can prevent 65-70 percent of these dangerous infections.

Dressings serve as a vital protective shield at the insertion site, creating an essential barrier against microbial colonization and environmental contaminants. When learning how to change a central line dressing, nurses must understand that maintaining clean, dry, and intact dressings is fundamental for preventing harmful microorganisms from entering the patient's bloodstream

Each time nursing professionals perform a sterile dressing change of a central line, it provides a crucial opportunity to thoroughly examine the site for early warning signs of infection or other complications.

Any unintended movement of the catheter can result in severe complications, including line failure and cardiovascular instability. For patients receiving critical care, these complications may significantly impact outcomes, potentially leading to increased morbidity and mortality rates. 

This highlights why proper dressing securement plays such a vital role in catheter stabilization and the prevention of displacement.

How often should you change the dressing?

Understanding the proper timing when learning how to change a central line dressing is essential. 

According to current guidelines, healthcare providers must change transparent semipermeable membrane (TSM) dressings at least every seven days. 

When using gauze dressings, more frequent changes become necessary—at a minimum—every 48 hours. The specific type of dressing material directly influences how often nurses need to perform a sterile dressing change of a central line.

However, nursing staff must know how to do a central line dressing change immediately if certain situations arise, such as:

  • The dressing becomes wet
  • The dressing is soiled
  • The dressing is loose
  • The dressing is dislodged. 

Many healthcare facilities now utilize chlorhexidine-impregnated dressings for adult patients. These specialized dressings have shown superior effectiveness in reducing catheter-related bloodstream infections compared to standard options. Between scheduled changes, these advanced dressings deliver ongoing protection by inhibiting bacterial growth around the insertion site.

For immunocompromised patients, proper dressing maintenance becomes even more critical. These vulnerable individuals face significantly higher infection risks during treatment, making proper technique essential when learning how to do a sterile dressing change of a central line.

Preparing for a dressing change

Success in central line dressing changes begins with proper preparation. This crucial step ensures maintaining strict infection prevention protocols throughout the entire procedure.

Gather the right supplies

Before beginning the central line dressing change, collect all necessary supplies, including:

  • Sterile and non-sterile gloves
  • Face masks (for provider and patient)
  • Chlorhexidine solution (two percent chlorhexidine with seventy percent alcohol)
  • Sterile transparent or gauze dressing
  • Biopatch (antimicrobial patch)
  • Sterile gauze
  • Adhesive tape
  • Documentation label

Many healthcare facilities provide convenient pre-packaged central line dressing kits containing most of the essential supplies needed for the procedure. 

For patients with known chlorhexidine sensitivities, povidone-iodine serves as an effective alternative antiseptic solution for maintaining sterility during the dressing change process.

Set up a clean workspace

When learning how to change a central line dressing, establishing a proper workspace is crucial for success. 

  • Select a clean, flat surface located away from potential contamination sources. Never use bathroom areas for this procedure, as these spaces contain excessive microorganisms that could compromise sterility. 
  • Clean your selected workspace thoroughly using either soap and water or an approved hospital-grade disinfectant solution. 
  • Create a sterile field by placing clean paper towels across the surface.
  • Ensure children and pets remain away from the designated workspace. 
  • Perform proper hand hygiene and restrict contact exclusively to the sterile supplies required for the dressing change.

If you touch any non-sterile items during the procedure, you must repeat the hand hygiene protocol completely.

Hand hygiene and mask requirements

When learning how to do a sterile dressing change of a central line, proper hand hygiene remains the cornerstone of preventing central line-associated bloodstream infections. 

Thoroughly cleanse hands with soap and water for no less than 20 seconds, paying special attention to areas between fingers and under fingernails. For nursing professionals learning how to change a central line dressing, alcohol-based hand sanitizers may serve as an acceptable alternative.

Both the healthcare provider and patient must don surgical masks before beginning the dressing change procedure. This essential safety measure helps prevent respiratory droplets from contaminating the sterile insertion site when performing a central line dressing change. 

For enhanced protection during nursing central line dressing changes, instruct patients to turn their head away from the site throughout the entire procedure.

Following these preparatory measures creates the foundation for a successful and sterile central line dressing change that minimizes infection risks.

Steps to change a central line dressing

When learning how to change a central line dressing, maintaining strict aseptic technique throughout the entire procedure is essential. 

Once preparation is complete, follow these crucial steps to minimize infection risk.

1. Remove the old dressing

Begin by donning clean gloves before handling the existing dressing. Carefully remove the dressing by pulling it perpendicular to the skin toward the insertion site.

Throughout removal, maintain a secure hold on the catheter to prevent accidental dislodgement. If the catheter adheres to the dressing, proceed with extra caution to maintain skin integrity. 

For adhesive securement devices, use alcohol to gently loosen the adhesive.

2. Inspect the site carefully

After dressing removal, thoroughly examine the site for potential infection signs or complications. Watch for concerning symptoms including redness, swelling, drainage, or unusual odor. 

Gently palpate around the insertion area to check for tenderness. This assessment proves crucial before proceeding further. 

Be sure to note the external catheter length to verify correct placement.

3. Clean with an antiseptic solution

Clean the insertion site meticulously using two percent chlorhexidine gluconate in 70 percent alcohol solution, which delivers extended antimicrobial protection.

Apply the antiseptic using steady back-and-forth motions for at least thirty seconds to thoroughly disinfect the area. Allow the solution to air dry completely, which typically requires about one minute. 

Never wipe or blot the site after application, as this can diminish the solution's effectiveness during nursing central line dressing changes.

4. Apply a new biopatch and dressing

Ensure the skin is entirely dry before proceeding with the following steps:

  • Position the biopatch antimicrobial disk with its blue printed surface facing up. 
  • Align the disk's slit with the catheter to achieve complete 360-degree contact between the disk and skin surrounding the insertion site. 
  • Apply the transparent dressing over both the catheter site and biopatch, starting from the top and working outward to eliminate air bubbles and ensure proper adhesion.

5. Secure the catheter and label the dressing

Properly secure the catheter using facility-approved methods to prevent movement. Many facilities utilize sutureless securement devices or adhesive stabilization devices for central line dressing changes. 

Press firmly around all edges of the transparent dressing to create an effective seal. 

Complete the procedure by labeling the dressing with the date, time, and your initials, ensuring compliance with facility protocols and tracking when the next dressing change is due.

Aftercare and monitoring

After completing the dressing change procedure, ongoing care and vigilant monitoring become vital aspects of central line maintenance. These final steps help ensure infection prevention and proper catheter function.

Dispose of used materials safely

Proper disposal of used materials is crucial for preventing cross-contamination.

Place all used gloves, old dressings, and other contaminated items in designated waste containers according to facility protocols. 

After disposal, thoroughly clean and disinfect your work surface using an approved hospital-grade disinfectant. Complete the waste management process by performing proper hand hygiene.

Check for signs of infection

Throughout central line placement, vigilant monitoring for infection indicators is essential. Central line-associated bloodstream infections remain one of the most serious hospital-acquired complications. Contact a physicianimmediately if you observe any of the following:

  1. Temperature elevation above 100.4 degrees Fahrenheit (38 degrees Celsius) or chills
  2. Redness, swelling, or tenderness at the insertion site
  3. Any drainage around the catheter area
  4. Unusual warmth at the site

When to change the injection caps

Learning how to change a central line dressing also includes understanding the proper timing for replacing injection caps (needleless connectors). 

These vital components require replacement every 96 hours to minimize infection risks, or sooner if blood or debris becomes visible inside. 

While some facilities synchronize cap changes with dressing changes, others strictly follow manufacturer recommendations, typically suggesting changes every 72 hours. During these replacements, maintaining proper aseptic technique remains crucial, including thorough scrubbing of the hub for a minimum of five seconds using an approved antiseptic pad.

Document the procedure

When performing a central line dressing change, thorough documentation completes the process. 

Your records should capture several essential elements, including the following: 

  • Procedure date and time
  • Detailed site assessment findings
  • Specific dressing type applied
  • Comprehensive evaluation observations 
  • Critical catheter measurements
  • Proper flushing procedures verified
  • Any complications encountered 

This detailed record-keeping fulfills multiple vital purposes, including meeting legal requirements, supporting insurance claims, and enhancing quality improvement initiatives.

Success with CVCs starts with attention to detail

Mastering the process of changing the sterile dressing on a central line represents a fundamental skill for ensuring patient safety and preventing infections. 

Understanding how often to change a central line dressing requires both theoretical knowledge and practical experience. 

While transparent dressings typically remain effective for seven days and gauze dressings require replacement every two days, any compromised dressing needs immediate attention regardless of the schedule. Regular site assessment during these changes provides valuable opportunities for early complication detection.

Most importantly, maintaining detailed documentation and strictly following facility protocols ensures seamless patient care delivery. The meticulous attention given to each step of changing a central line dressing—from proper hand hygiene through thorough site cleansing to precise dressing application—collectively contributes to effective central line management. 

For additional guidance on other healthcare topics, explore the Nursa blog for a variety of comprehensive resources.

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Nursa Admin
Blog published on:
July 23, 2025

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